Agenda
Agenda
8:30 AM Registration / Check-in Begins
9:00 AM Opening Remarks
Lorraine Stiehl, ALF
Sangeeta Bhatia, MD, PhD, Massachusetts Institute of Technology
9:20 AM Spatially Resolved Single Cell Genomics
Xiaowei Zhuang, PhD, Harvard University
9:45 AM Beyond Classical Hepatology: Curing a Neurological Disease Through the Liver
Karl-Dimiter Bissig, MD, PhD, Duke University
10:10 AM Trainee Microtalks
10:25 AM Morning Break
10:45 AM Perturb-Multi: Multimodal Genetic Screens in the Intact Liver Reveal the Control of Hepatocyte Zonation, ER Stress, and Steatosis
Jonathan Weissman, PhD, Massachusetts Institute of Technology
11:10 AM Nucleic Acid Sensing Pathways as Drivers of Immunity and Inflammation
Kate Fitzgerald, PhD, UMass Chan Medical School
11:35 AM Technical Push or Clinical Pull? Innovation in Liver Transplantation
Yanik Bababekov, MD, Tufts University
12:00 PM Trainee Microtalks
12:15 PM Lunch — Poster Viewing & Judging
1:45 PM Identification and Treatment of Patients with MASH and Liver Fibrosis: the Resmetirom Story and Beyond
Rebecca Taub, MD, PhD, Madrigal Pharmaceuticals
2:10 PM Liver Lymphatics in Health and Disease
Yasuko Iwakiri, PhD, Yale University
2:35 PM Trainee Microtalks
2:50 PM Afternoon Break
3:10 PM The Organelle, Cell, and Tissue Mechanics Driving MASLD Progression
Becky Wells, PhD, University of Pennsylvania
3:35 PM Identifying & Counteracting the Impact of Environmental Stress on Tissue Function
Alex Shalek, PhD, Massachusetts Institute of Technology
4:00 PM New Genetic Tools for Measuring and Manipulating Metabolism
Vamsi Mootha, MD, Massachusetts Institute of Technology
4:25 PM Closing Remarks & Awards Presentations
Wolfram Goessling, MD, PhD, Yale School of Medicine
4:30 PM Wine & Cheese Reception
Join this one-day virtual event to hear from leading biomedical scientists and physicians as they present critical research bridging basic science and liver disease.
Plenary speakers include:
Adjoa Anyane-Yeboa, MD MPH
Institution: Division of Gastroenterology Department of Medicine Massachusetts General Hospital Harvard Medical School
Lew Cantley, PhD
Institution: Dana Farber Cancer Institute
Presentation Title: Altered liver metabolism confounds the effectiveness of PI3K inhibitors for treating breast and endometrial cancers
Hans Clevers, PhD
Institution: Roche/Hubrecht Institute
Presentation Title: Organoids to model human diseases
Nikla Emambokus, PhD
Institution: Editor-in-Chief, Med; Executive Editor Med, Cell Metabolism
Heather Francis, PhD
Institution: Indiana University
Presentation Title: Regulation of Chronic Liver Disease and Cholangiopathies by Mast Cells
Stacey Huppert, PhD
Institution: Cincinnati Children’s
Presentation Title: Hepatic Epithelial Development and Plasticity- Identity and Commitment
Sonja Schrepfer, MD, PhD
Institution: Cincinnati Children’s
Presentation Title: Protecting transplanted cells from immune rejection is the key to unlocking the potential of regenerative medicine
Bao-Liang Song, PhD
Institution: Wuhan University
Presentation Title: Inhibition of ASGRI decreases lipid levels by promoting cholesterol excretion
Elizabeth K Speliotes MD, PhD, MPH
Institution: University of Michigan
Presentation Title: Genetic Subtyping of NAFLD
Joseph Takahashi, PhD
Institution: UT Southwestern
Presentation Title: Circadian clocks and their importance for metabolism, aging and longevity
Giovanni Traverso, MD, PhD
Institution: MIT, Brigham & Women’s Hospital, Harvard Medical School
Presentation Title: Explant liver model for drug development
Aubrey Weigel, PhD
Institution: Howard Hughes Medical Institute
Presentation Title: Towards Automatic Segmentation of Organelles in vEM
Hao Zhu, MD, PhD
Institution: UT Southwestern
Presentation Title: Clone Wars: Evolution of Adaptation and Malignancy in the liver
Hosted by:
- Sangeeta Bhatia, MD, PhD – Massachusetts Institute of Technology
- Wolfram Goessling, MD, PhD – Massachusetts General Hospital